Rosh Internal Medicine Boost Practice Exam

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What symptom is most commonly associated with hypercalcemia in patients?

Constipation
Diarrhea
Bradycardia
Weight loss

The correct answer is: Constipation

Hypercalcemia, which refers to an elevated level of calcium in the blood, often presents with various symptoms. Among these, constipation is the most commonly associated symptom. The mechanism behind this is related to the effects of high calcium levels on the gastrointestinal tract. Calcium can slow down intestinal motility, leading to a decrease in bowel movements and resulting in constipation. While other symptoms can occur with hypercalcemia, such as fatigue, nausea, and abdominal pain, constipation stands out as a frequent occurrence due to its direct impact on the digestive system's functioning. Understanding this association can be crucial for clinicians when diagnosing and managing hypercalcemia, as it directs attention to gastrointestinal health in patients presenting with elevated calcium levels.